Salvage-radiotherapy for biochemical recurrence of prostate cancer – with or without hormonal ablation?
نویسنده
چکیده
The only curative therapeutic option for patients with BR is the so-called salvage radiotherapy (SRT). However, about 50% of the patients will experience a biochemical (as a reliable surrogate for tumor control) or a clinical recurrence after SRT within the following five years [3]. Retrospective analyses revealed PSA level before SRT and dose of SRT as the most significant risk factors for failure after SRT, followed by pathological stage, resection margin, or Gleason sum score [4].
منابع مشابه
Salvage local therapy for radiation-recurrent prostate cancer – where are we?
INTRODUCTION Prostate cancer is the most frequent cancer among males in Europe and a leading cause of cancer deaths, with similar proportion in other developed countries. For more than twenty years, external-beam radiation therapy, alongside with radical prostatectomy, has been used as a primary radical therapeutic approach for localized prostate cancer. Yet, EBRT failures relate to 22-69% foll...
متن کاملSignificance of early prostate-specific antigen values after salvage radiotherapy in recurrent prostate cancer patients treated with surgery.
OBJECTIVES To assess the use of post-salvage radiotherapy prostate-specific antigen for early prediction of biochemical failure or clinical recurrence after salvage radiotherapy in recurrent prostate cancer patients after prostatectomy. METHODS From 2000 to 2011, 164 patients were treated with salvage radiotherapy alone for recurrent prostate cancer. Patients who received androgen deprivation...
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Fifty-three patients with biochemical relapse (BCR) after receiving external beam radiotherapy (EBRT) against locally advanced prostate cancer (stage III : International Union Against Cancer [UICC] 6th edition) between September 1997 and January 2006 at our institution, who were treated with salvage hormonal therapy (HTx), were followed for a mean period of 75.5 months. There was progression to...
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متن کاملMortality and Androgen Deprivation Therapy as Salvage Treatment for Biochemical Recurrence after Primary Therapy for Clinically Localized Prostate Cancer.
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